RSC Adv., 2014, 4, 22106-22114
DOI: 10.1039/C4RA01689K
Received 26 Feb 2014,
Accepted 02 May 2014
First published online 07 May 2014
Abstract
The synthesis of pyrimidinone containing bisheteroarenes (3) and related analogs (9 and 10) by the reaction of active methylenes or substituted methyl acrylate with nitrogen containing precursors viz amidines, or thiourea in water as well as other organic solvents was studied. Synthesized compounds had further been explored for the synthesis of diversified pyrimidines 4, 6-8, 11-12 and 14 through sequential approach.
