RSC Adv., 2013,3, 12955-12962
DOI: http://dx.doi.org/10.1039/C3RA41575A
A regio selective synthesis of 2,6-diarylpyridines through base (sodium hydroxide in DMSO) catalyzed ring transformation of suitably functionalized 2H-pyran-2-ones with benzamide has been delineated. However, similar reaction of 2H-pyran-2-ones with benzamide using base sodium hydroxide in absolute ethanol have yielded highly congested delta keto esters with active methylene centre instead of 2,6-diarylpyridines.
